Indeterminate pulmonary nodules in colorectal cancer

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The frequency and significance of radiologically detected indeterminate pulmonary nodules in patients with colorectal cancer.

OBJECTIVE To investigate the frequency and significance of pulmonary nodules in patients with colorectal cancer (CRC). SUBJECTS AND METHODS Medical records of 1,344 patients with CRC who underwent thoracic computerized tomography scans between January 2003 and December 2009 were reviewed. Those with any distant metastatic disease or who were already known to have pulmonary malignancies were e...

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Pulmonary nodules and metastases in colorectal cancer.

Patients with newly diagnosed colorectal cancer (CRC) are subjected to a preoperative thoraco-abdominal CT scan to determine the cancer stage. This staging is of relevance with regard to treatment and prognosis. About 20% of the patients have distant metastatic spread at the time of diagnosis, i.e. synchronous metastases. Most common are hepatic metastases followed by pulmonary involvement. The...

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Sputum microRNA biomarkers for identifying lung cancer in indeterminate solitary pulmonary nodules.

PURPOSE The early detection of lung cancer in heavy smokers by low-dose CT (LDCT) can reduce the mortality. However, LDCT screening increases the number of indeterminate solitary pulmonary nodules (SPN) in asymptomatic individuals, leading to overdiagnosis. Making a definitive preoperative diagnosis of malignant SPNs has been a clinical challenge. We have demonstrated that sputum miRNAs could p...

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Biology of Human Tumors Sputum microRNA Biomarkers for Identifying Lung Cancer in Indeterminate Solitary Pulmonary Nodules

Purpose:The early detectionof lung cancer inheavy smokers by low-dose CT (LDCT) can reduce the mortality. However, LDCT screening increases the number of indeterminate solitary pulmonary nodules (SPN) in asymptomatic individuals, leading to overdiagnosis. Making a definitive preoperative diagnosis of malignant SPNs has been a clinical challenge. We have demonstrated that sputum miRNAs could pro...

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Video Assisted Thoracic Surgery for Indeterminate Pulmonary Nodules

The approach to patients with indeterminate pulmonary nodules is poorly defined. Should every pulmonary nodule be biopsied, is needle biopsy adequate, and other questions are challenges. Video assisted thoracic surgery or thoracoscopy has added a new diagnostic possibility which is evaluated in this paper. Fifty-five patients underwent thoracoscopy for diagnosis of a solitary pulmonary nodule. ...

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 2015

ISSN: 1007-9327

DOI: 10.3748/wjg.v21.i10.2967